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Mescaline or 3,4,5-trimethoxyphenethylamine is a
psychedelic hallucinogenic drug and entheogen of the phenethylamine
family. It is either synthesized (as mesacline sulfate) or extracted
from the peyote cactus (Lophophora williamsii), the San Pedro cactus (Echinopsis
pachanoi), or the Peruvian Torch cactus (Echinopsis peruviana). It is
also found in a number of other members of the Cactaceae.
The use of extract from peyote in Native American religious ceremonies
has been noted since the earliest European contact, notably by the
Huichols in Mexico. It was first isolated and identified in 1897 by the
German Arthur Heffter and first synthesized in 1919. The effective human
dosage is 200–400 milligrams (3.75 mg/kg), with the effects lasting for
up to twelve hours. It is not physically addictive. In the US it was
made illegal in 1970 by the Comprehensive Drug Abuse Prevention and
Control Act. It was prohibited internationally by the 1971 Convention on
Psychotropic Substances and is categorised as a Schedule I hallucinogen
by the CSA. Users typically experience visual hallucinations and
radically altered states of consciousness, often experienced as
pleasurable and illuminating but occasionally as accompanied by feelings
of anxiety or revulsion.
Negative Side Effects
- Dizziness
- Vomiting
- Tachycardia
- Headaches
- Anxiety
- Feeling of dying or annihilation
- Fear of not being able to return to normal consciousness
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